How to Troubleshoot “The set of folders cannot be opened” Issue on Outlook

Businesses and individuals often use Outlook as an e-mail client because it is easy to use and integrates with MS Office and other Microsoft products. It also offers the ability to connect to Exchange, which is useful for corporate email.

Although it is a popular e-mail client, there are often many bugs when using it. However, the most common error they encounter is “Cannot open folder group.” This error is often an obstacle for users when they want to access their Outlook messages and emails.

What is the cause of “Folder group cannot be opened”?

  • The main reason is a corrupt Outlook profile file – the .xml file named Outlook.
  • Another reason could be that Outlook is trying to work in compatibility mode or that you are using a profile file (.pst or .ost) created in an older version of Outlook that has been deleted or corrupted.

How to eliminate the “Can’t open folder set” message?

Exporting your profile from the registry

  1. Press the Windows + R keys and type Regedit. Press Enter or press OK.
  2. On the left side of the window, navigate to
  3. Right-click on the Profile key and choose Export from the menu.
  4. Select a safe location for the file, name it profile.reg and click Save.
  5. Now find the file profile.reg, right-click it, and choose Edit from the menu.
  6. When notepad opens, replace 15.0 with 16.0 everywhere in the file.
  7. Then save your changes.
  8. Now find the file profile.reg and run it.
  9. A confirmation message will appear on the screen. Click Yes to continue.

Deleting .xml files from the Outlook directory

  1. Press Windows + R and type appdata. Press Enter or press OK.
  2. When the AppData directory opens, go to LocalMicrosoftOutlook16*.
  3. Now find all the .xml files and delete them.

Launch Outlook as an administrator and turn off compatibility mode

  1. Find the Outlook shortcut, right-click on it and choose Properties from the menu.
  2. Click the Compatibility tab and disable the option Run this program in compatibility mode.
  3. Now turn on the option Run this program as administrator and click Apply and OK to save your changes.

Restore the Office installation

  1. Open the Control Panel and go to Programs and Features.
  2. When the Programs and Features window opens, select Microsoft Office from the list of applications and click the Edit button at the top.
  3. Then select the Quick Fix option.
  4. Follow the instructions on the screen to complete the repair.

Launching Outlook in Safe Mode

  1. Press the Windows + R keys and type Outlook /safe. Press Enter or press OK.
  2. If you run Outlook in safe mode, you must disable your add-ons. To do this, click File > Options > Add-ons.
  3. Then click the Go button next to Manage: Com-in Add.
  4. Disable all available add-ons and click OK to save your changes.

Creating a new Outlook profile

  1. Open the Control Panel. To do this, press the Windows + S keys and open the Control Panel.
  2. Now select Control Panel from the list of results.
  3. Go to the Mail section. If you can’t find it, go to User Accounts > Mail.
  4. Now click View Profiles.
  5. Select your profile and click Delete.
  6. In the Mail Profiles window, click Add and enter a name for the new Outlook profile.
  7. Click OK to save your changes.
  8. Now select Automatic Account Setup or Manual Setup and follow the on-screen instructions to complete the process.

Frequently Asked Questions

  1. Create a new Outlook profile.
  2. Use a shortcut on the taskbar to launch Outlook.
  3. Make sure that you use a separate password for Outlook.
  4. Log out of iCloud.
  5. Reinstall iCloud.
  6. Do not install the cumulative Exchange Server update.
  7. Make sure you have installed the 64-bit version of Office.

The folder pane shows all folders in Outlook. If the folder bar is minimized, you cannot see your folders. Expand the folder bar by clicking the -> icon on the left side of the screen. Click View -> Folder Panel -> Normal.

  1. Click Folder at the bottom of the left pane in Outlook.
  2. Go to "Deleted Items" and click on the drop-down list to find your folder.